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8-Aza-ATP is a structural analog of ATP characterized by the substitution of the carbon atom at the 8-position of the purine ring with nitrogen resulting in an 8-azapurine nucleotide moiety Due to this structural alteration 8-Aza-ATP competitively interacts with ATP-binding sites on enzymes thereby modulating their catalytic activities This compound serves as a tool in biochemical research to elucidate enzyme-substrate recognition nucleotide binding specificity and catalytic mechanisms of ATP-dependent enzymes Additionally it is utilized in the study of cellular energy metabolism signal transduction pathways and nucleotide-mediated regulatory processes contributing to understanding relevant physiological and pathological mechanisms
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2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
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Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid intestinal cells blood-brain barrier and in brain microvessels.
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GTP also known as Guanosine-5 -triphosphate can be utilized in various molecular biology applications such as in vitro transcription RNA amplification and siRNA synthesis Additionally GTP plays a critical regulatory role in signal transduction as a phosphate or pyrophosphate messenger it activates G-proteins which subsequently initiate protein kinase-mediated signaling cascades thus influencing cellular behaviors including cell proliferation and differentiation GTP also serves as a high-energy nucleotide precursor participating in enzymatic synthesis processes of DNA and RNA This product is prepared from GTP trisodium salt with purity 99% (HPLC) as a clear colorless aqueous solution at a concentration of 100 mM and pH (25 C) of 7 0 0 1 free from DNase and RNase contamination
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Alpha guanosine is a purine nucleoside analog used in biochemical and pharmacological research to study nucleoside metabolism and antimetabolite activity. The product is supplied as a purified powder with documented physicochemical properties, recommended storage conditions, and solubility information to support preparation of stable stock solutions for laboratory use.
Purity: 95.96%
Molecular formula: C10H13N5O5
Molecular weight: 283.24 g/mol
Soluble in DMSO at 12.5 mg/mL with ultrasonic warming to 60°C
Powder recommended storage: -20°C, stable for up to 3 years
In-solution stability: -80°C for 6 months, -20°C for 1 month
Available in small milligram pack sizes for research applications
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